September 16, 2020

2 Doktoranden gesucht (Experimentelle und Klinische Pharmakologie und Toxikologie, Medizinische Fakultät der UdS, Homburg) english version below

Sie haben einen Masterabschluss/Examen in Biologie, Pharmazie, Humanbiologie, Biochemie, Chemie oder eng verwandten Disziplinen, besitzen eine Leidenschaft für die Wissenschaft, sind zuverlässig und motiviert?

Wir suchen ab sofort für die Beschäftigungsdauer von 3 Jahren zwei Wissenschaftliche Mitarbeiter/Mitarbeiterinnen (m/w/d) zur Durchführung einer Dissertationsarbeit (zum Dr. rer. nat.). Im Rahmen der Forschungsprojekte arbeiten Sie in einem Team mit erfahrenen Wissenschaftlern und haben die Möglichkeit, modernste analytische Methoden zu erlernen und Ihre Fähigkeiten zu verbessern. Eine intensive Einarbeitung und Betreuung ist selbstverständlich.

Projekt I beschäftigt sich mit dem Einfluss des TRPV6 Ionenkanals auf Calcium-abhängige Prozesse im weiblichen Fortpflanzungstrakt und der Eihaut. Ansprechpartner ist Frau Dr. Claudia Fecher-Trost (

In Projekt II geht es um die pharmakologische Beeinflussbarkeit der zellulären Ca2+-Homöostase. Ansprechpartner ist Herr Dr. Andreas Beck (

Wenn wir Ihr Interesse geweckt haben, kontaktieren Sie uns bzw. senden Sie uns Ihre Bewerbungsunterlagen.

You have a master’s degree/exam in biology, pharmacy, human biology, biochemistry, chemistry or closely related disciplines, are passionate about science, reliable and motivated?

We are looking for two doctoral candidates (m/f/d) for a period of 3 years. As part of the research project, you will work in a team with experienced scientists and have the opportunity to learn the most modern analytical methods and improve your skills. Intensive training and support is a matter of course.

Project I focuses on the influence of the TRPV6 ion channel on calcium-dependent processes in the female reproductive tract and the fetal membrane. Contact: Dr. Claudia Fecher-Trost (
Project II is about the pharmacological modulation of the cellular Ca2+ homeostasis. Contact: Dr. Andreas Beck (

If you are interested, please contact us or send us your application documents.


January 27, 2020

PhD position (Medical Biochemistry & Molecular Biology): Biogenesis and Function of Lipid Droplets

We are looking for a highly motivated scientist to join our young and growing team as a PhD student.

The position is immediately available at the
Department of Medical Biochemistry & Molecular Biology
Center for Molecular Signaling (PZMS)
at Saarland University
in the research group of
Jun.-Prof. Dr. Bianca Schrul.

Our research group is interested in the biogenesis and function of lipid droplets. These subcellular organelles dynamically balance the influx, storage and consumption of neutral lipids in nearly all cells of our body and are therefore central hubs in lipid metabolism. Lipid droplets are implicated in a range of human pathologies including hallmark diseases of our modern society such as obesity, diabetes, hepatic steatosis and cardiovascular disorders. However, the molecular mechanisms underlying lipid droplet biogenesis and function as well as pathologic aberrations in these processes remain largely unknown. Projects in our lab address the following questions:

• What are the molecular mechanisms underlying protein targeting and insertion into the limiting membrane of lipid droplets?
• How is lipid droplet biogenesis from the endoplasmic reticulum membrane regulated?
• How do lipid droplets communicate with other lipid metabolizing organelles to adapt to metabolic changes?

We employ a range of biochemical and cell biological techniques including in vitro reconstitution experiments, protein-interaction studies, organelle / protein isolations, CRISPR/Cas9 genome editing, RNA interference as well as advanced fluorescence and electron microscopy.

Further information and publications can be found on our website:

Qualification profile
We are looking for a highly motivated scientist with the following qualifications:
– excellent Diploma / M.Sc. degree in Biochemistry, Molecular Biology or a related discipline
– strong interest in basic Biochemical and Cell Biological research
– excellent communication skills
– fluent English (oral and written) is essential
– German language skills are desired

– Our young research team is integrated in an interdisciplinary and diverse research environment offering state-of-the-art technology and excellent scientific exchange.
– Further training opportunities are provided by Saarland University´s Graduate Centre GradUS.
– The position is immediately available for the duration of 3 years with the possibility of extension.

Please send your application including a short cover letter stating your research interests, a CV, degree certificates and contacts for two references via e-mail to Jun.-Prof. Dr. Bianca Schrul: